Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | QDPR | P09417 | 3/20 | 0.68 |
| ▸ | NPC1 | O15118 | 1/20 | 0.58 |
| ▸ | RAB9A | P51151 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | HTR1A | P08908 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.50 |
| ▸ | HTR6 | P50406 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16862164 | 0.96 | QDPR (0.67) | QDPRNPC1RAB9AKMT2AKDM4E | |
| SCHEMBL50923 | 0.96 | QDPR (0.67) | QDPRNPC1RAB9AKMT2AKDM4E | |
| Ammonia Solution, Strong SCHEMBL15875021 | 0.94 | QDPR (0.65) | QDPRNPC1RAB9AKMT2AKDM4E | |
| Bromide SCHEMBL11557389 | 0.94 | QDPR (0.65) | QDPRNPC1RAB9AKMT2AKDM4E | |
| Hydrochloric Acid SCHEMBL1148906 | 0.94 | QDPR (0.65) | QDPRNPC1RAB9AKMT2AKDM4E | |
| Hydrochloric Acid SCHEMBL19717522 | 0.92 | QDPR (0.62) | QDPRKDM4ELMNAPOLBHTR1A | |
| SCHEMBL16565762 | 0.85 | QDPR (0.53) | QDPRNPC1RAB9AKMT2A | |
| Hydrochloric Acid SCHEMBL6517404 | 0.84 | QDPR (0.50) | QDPRNPC1RAB9AKMT2AKDM4E | |
| SCHEMBL7369176 | 0.84 | QDPR (0.72) | QDPRSLC6A4 | |
| SCHEMBL13591401 | 0.83 | QDPR (0.49) | QDPRNPC1RAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7498344-B2 | Arylpiperidinol and arylpiperidine derivatives and pharmaceuticals containing the same | ASUBIO PHARMA CO., LTD. (JP) | 2009-03-03 | — | — | US | disclosed |