Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.56 |
| ▸ | ABCB1 | P08183 | 7/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.53 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.53 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | DRD2 | P14416 | 3/20 | 0.51 |
| ▸ | DRD4 | P21917 | 3/20 | 0.51 |
| ▸ | DRD3 | P35462 | 3/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13898527 | 0.90 | L3MBTL1 (0.63) | L3MBTL1KDM4ECYP2D6TSHRHIF1A | |
| SCHEMBL13898292 | 0.89 | L3MBTL1 (0.69) | L3MBTL1KDM4ECYP2D6TSHRHIF1A | |
| SCHEMBL13898525 | 0.84 | L3MBTL1 (0.56) | L3MBTL1KDM4ECYP2D6TSHRHIF1A | |
| SCHEMBL13898288 | 0.82 | L3MBTL1 (0.63) | L3MBTL1KDM4ECYP2D6TSHRHIF1A | |
| SCHEMBL2027615 | 0.82 | ABCB1 (0.61) | L3MBTL1KDM4ECYP2D6TSHRHIF1A | |
| SCHEMBL2027614 | 0.82 | ABCB1 (0.61) | L3MBTL1KDM4ECYP2D6TSHRHIF1A | |
| SCHEMBL7969310 | 0.82 | L3MBTL1 (0.51) | L3MBTL1KDM4ECYP2D6TSHRHIF1A | |
| SCHEMBL11812283 | 0.81 | L3MBTL1 (0.61) | L3MBTL1KDM4ECYP2D6TSHRHIF1A | |
| SCHEMBL16808047 | 0.81 | ABCB1 (0.63) | L3MBTL1KDM4ECYP2D6TSHRHIF1A | |
| SCHEMBL16808048 | 0.81 | ABCB1 (0.63) | L3MBTL1KDM4ECYP2D6TSHRHIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7498344-B2 | Arylpiperidinol and arylpiperidine derivatives and pharmaceuticals containing the same | ASUBIO PHARMA CO., LTD. (JP) | 2009-03-03 | — | — | US | disclosed |
| US-7498344-B2 | Arylpiperidinol and arylpiperidine derivatives and pharmaceuticals containing the same | ASUBIO PHARMA CO., LTD. (JP) | 2009-03-03 | — | — | US | disclosed |