Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 6/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13899180 | 0.85 | TSHR (0.36) | TSHRGAAALDH1A1TP53HIF1A | |
| SCHEMBL13899372 | 0.84 | TSHR (0.40) | TSHRALDH1A1TP53HIF1ACYP3A4 | |
| SCHEMBL13899170 | 0.82 | TSHR (0.35) | TSHRGAAALDH1A1TP53HIF1A | |
| SCHEMBL21950054 | 0.79 | EPHX1 (0.46) | TSHRALDH1A1TP53HIF1ACYP3A4 | |
| SCHEMBL5663537 | 0.77 | TSHR (0.56) | TSHRALDH1A1TP53HIF1ACYP3A4 | |
| SCHEMBL12570601 | 0.75 | TSHR (0.54) | TSHRALDH1A1TP53HIF1ACYP3A4 | |
| SCHEMBL13899179 | 0.74 | TSHR (0.43) | TSHRALDH1A1TP53HIF1ACYP3A4 | |
| SCHEMBL21950073 | 0.73 | TSHR (0.36) | TSHRALDH1A1TP53HIF1ACYP3A4 | |
| SCHEMBL13051495 | 0.72 | TSHR (0.36) | TSHRGAAALDH1A1TP53HIF1A | |
| SCHEMBL12570592 | 0.71 | TSHR (0.64) | TSHRALDH1A1TP53HIF1ACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7498394-B2 | (Meth)acrylic and (meth)acrylamide monomers, polymerizable compositions, and polymers obtained | THE REGENTS OF THE UNIVERSITY OF COLORADO (US) | 2009-03-03 | — | — | US | disclosed |
| US-7498394-B2 | (Meth)acrylic and (meth)acrylamide monomers, polymerizable compositions, and polymers obtained | THE REGENTS OF THE UNIVERSITY OF COLORADO (US) | 2009-03-03 | — | — | US | disclosed |