Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 6/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13051495 | 0.85 | TSHR (0.36) | TSHRGAAALDH1A1TP53HIF1A | |
| SCHEMBL13899179 | 0.82 | TSHR (0.43) | TSHRALDH1A1TP53HIF1ACYP3A4 | |
| SCHEMBL13714844 | 0.82 | TSHR (0.42) | TSHRALDH1A1TP53HIF1ACYP3A4 | |
| SCHEMBL13899138 | 0.82 | TSHR (0.35) | TSHRGAAALDH1A1TP53HIF1A | |
| SCHEMBL13899372 | 0.82 | TSHR (0.40) | TSHRALDH1A1TP53HIF1ACYP3A4 | |
| SCHEMBL24031881 | 0.80 | ALDH1A1 (0.41) | TSHRALDH1A1TP53HIF1ACYP3A4 | |
| SCHEMBL18467741 | 0.77 | TSHR (0.41) | TSHRALDH1A1TP53HIF1ACYP3A4 | |
| SCHEMBL29206162 | 0.75 | TSHR (0.34) | TSHRALDH1A1TP53HIF1ACYP3A4 | |
| SCHEMBL12111976 | 0.74 | TSHR (0.57) | TSHRALDH1A1TP53HIF1ACYP3A4 | |
| SCHEMBL13872046 | 0.74 | TSHR (0.57) | TSHRALDH1A1TP53HIF1ACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7498394-B2 | (Meth)acrylic and (meth)acrylamide monomers, polymerizable compositions, and polymers obtained | THE REGENTS OF THE UNIVERSITY OF COLORADO (US) | 2009-03-03 | — | — | US | disclosed |
| US-7498394-B2 | (Meth)acrylic and (meth)acrylamide monomers, polymerizable compositions, and polymers obtained | THE REGENTS OF THE UNIVERSITY OF COLORADO (US) | 2009-03-03 | — | — | US | disclosed |