Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | HTT | P42858 | 3/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.46 |
| ▸ | KDR | P35968 | 1/20 | 0.46 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 3/20 | 0.44 |
| ▸ | BCHE | P06276 | 2/20 | 0.43 |
| ▸ | ACHE | P22303 | 2/20 | 0.43 |
| ▸ | TNF | P01375 | 1/20 | 0.42 |
| ▸ | HTR3A | P46098 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13899522 | 0.86 | KDR (0.59) | ALDH1A1MAPTKDM4EMEN1KMT2A | |
| SCHEMBL13202490 | 0.81 | ADORA2A (0.55) | ALDH1A1MAPTKDM4EMEN1KMT2A | |
| SCHEMBL29923672 | 0.79 | ALDH1A1 (0.47) | ALDH1A1MAPTKDM4EMEN1KMT2A | |
| SCHEMBL14737989 | 0.79 | ALDH1A1 (0.47) | ALDH1A1MAPTKDM4EMEN1KMT2A | |
| SCHEMBL2320642 | 0.79 | ALDH1A1 (0.47) | ALDH1A1MAPTKDM4EMEN1KMT2A | |
| SCHEMBL20389037 | 0.79 | NAMPT (0.52) | ALDH1A1MAPTKDM4EMEN1KMT2A | |
| SCHEMBL3655093 | 0.78 | PRKCI (0.41) | ALDH1A1MAPTKDM4EMEN1KMT2A | |
| SCHEMBL24915548 | 0.77 | KDM4E (0.45) | ALDH1A1MAPTKDM4EMEN1KMT2A | |
| SCHEMBL10271494 | 0.77 | HSD17B10 (0.45) | ALDH1A1MAPTKDM4EMEN1KMT2A | |
| SCHEMBL10221610 | 0.77 | MAPT (0.45) | ALDH1A1MAPTKDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023186773-A1 | SUBSTITUTED 3-AMINO INDAZOLE DERIVATIVES AS KINASE INHIBITORS | NERVIANO MEDICAL SCIENCES S.R.L. (IT) | 2023-10-05 | — | — | WO | disclosed |
| US-7511136-B2 | Aminoindazole derivatives active as kinase inhibitors | PFIZER ITALIA S.R.L. (IT) | 2009-03-31 | — | — | US | disclosed |