SCHEMBL13899892

SCHEMBL13899892

C=CC(=O)Oc1cc(CCCCCCCCCCCC)cc(OC(=O)C=C)c1OC(=O)C=C

nearest known ligand 0.61

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
THRB P10828 9/20 0.61
THRA P10827 7/20 0.59
MEN1 O00255 1/20 0.48
KMT2A Q03164 1/20 0.48
PPARA Q07869 2/20 0.44
PPARG P37231 1/20 0.44
GPR84 Q9NQS5 2/20 0.43
PTGS2 P35354 3/20 0.42
CYP3A4 P08684 1/20 0.40
ALOX5 P09917 1/20 0.39
HPGD P15428 1/20 0.39
TSHR P16473 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4645645 0.84 THRB (0.59) THRBTHRAMEN1KMT2AGPR84
SCHEMBL4647837 0.84 THRB (0.59) THRBTHRAMEN1KMT2AGPR84
SCHEMBL13899888 0.84 THRB (0.70) THRBTHRAMEN1KMT2APPARA
SCHEMBL29046994 0.80 THRB (0.53) THRBTHRAMEN1KMT2APPARA
SCHEMBL30037836 0.80 THRB (0.61) THRBTHRAMEN1KMT2APPARA
SCHEMBL31542119 0.79 THRB (0.56) THRBTHRAMEN1KMT2AGPR84
SCHEMBL27662663 0.79 THRB (0.63) THRBTHRAMEN1KMT2APPARA
SCHEMBL29046999 0.79 THRB (0.51) THRBTHRAMEN1KMT2AALOX5
SCHEMBL3412317 0.78 THRB (0.55) THRBTHRAMEN1KMT2AGPR84
SCHEMBL2289080 0.78 THRB (0.97) THRBTHRAMEN1KMT2APTGS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7501166-B2 Liquid crystal panel and manufacturing method therefor SHARP KABUSHIKI KAISHA (JP) 2009-03-10 US disclosed
US-7279203-B2 Liquid crystal panel SHARP KABUSHIKI KAISHA (JP) 2007-10-09 US disclosed