Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 5/20 | 0.49 |
| ▸ | HDAC4 | P56524 | 5/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 5/20 | 0.49 |
| ▸ | HDAC2 | Q92769 | 5/20 | 0.49 |
| ▸ | HDAC10 | Q969S8 | 5/20 | 0.49 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 5/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 5/20 | 0.49 |
| ▸ | HDAC9 | Q9UKV0 | 5/20 | 0.49 |
| ▸ | HDAC7 | Q8WUI4 | 4/20 | 0.49 |
| ▸ | HDAC5 | Q9UQL6 | 4/20 | 0.49 |
| ▸ | NCOR2 | Q9Y618 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17767811 | 0.90 | EPHX2 (0.61) | LMNATSHREPHX2HTTL3MBTL1 | |
| SCHEMBL17767806 | 0.90 | EPHX2 (0.61) | LMNATSHREPHX2HTTL3MBTL1 | |
| SCHEMBL26315834 | 0.88 | LMNA (0.64) | LMNATSHREPHX2HTTL3MBTL1 | |
| SCHEMBL18743946 | 0.86 | HPGD (0.58) | LMNATSHREPHX2HTTL3MBTL1 | |
| SCHEMBL13901153 | 0.86 | HTT (0.44) | LMNATSHREPHX2HTTL3MBTL1 | |
| SCHEMBL24414987 | 0.86 | HPGD (0.61) | LMNATSHREPHX2L3MBTL1HPGD | |
| SCHEMBL20334484 | 0.85 | HDAC3 (0.50) | LMNATSHREPHX2HTTL3MBTL1 | |
| SCHEMBL17589268 | 0.85 | HPGD (0.52) | LMNATSHREPHX2HTTL3MBTL1 | |
| SCHEMBL17599911 | 0.84 | EPHX2 (0.56) | LMNATSHREPHX2HTTL3MBTL1 | |
| SCHEMBL18703881 | 0.84 | EPHX2 (0.56) | LMNATSHREPHX2HTTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7507859-B2 | Functional synthetic molecules and macromolecules for gene delivery | FIFTH BASE LLC (US) | 2009-03-24 | — | — | US | disclosed |