Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 8/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.31 |
| ▸ | TP53 | P04637 | 2/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11118154 | 0.98 | TSHR (0.37) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL110060 | 0.98 | TSHR (0.37) | TSHRHPGDALDH1A1TP53HIF1A | |
| Cyclopropane SCHEMBL29098034 | 0.93 | TSHR (0.34) | TSHRHPGD | |
| SCHEMBL28078305 | 0.93 | TSHR (0.34) | TSHRHPGD | |
| SCHEMBL21670465 | 0.92 | TSHR (0.33) | TSHRHPGD | |
| Butanone SCHEMBL28280023 | 0.92 | TSHR (0.33) | TSHRHPGDALDH1A1 | |
| SCHEMBL20603539 | 0.90 | TSHR (0.33) | TSHRHPGD | |
| SCHEMBL5448475 | 0.88 | ALDH1A1 (0.32) | TSHRHPGDALDH1A1 | |
| SCHEMBL29249892 | 0.87 | TSHR (0.36) | TSHRHPGD | |
| SCHEMBL28289488 | 0.86 | TSHR (0.37) | TSHRHPGDALDH1A1TP53HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020067046-A1 | SEALING AGENT FOR ORGANIC ELECTROLUMINESCENT DISPLAY ELEMENTS | デンカ株式会社 | 2020-04-02 | — | — | WO | disclosed |
| EP-2424740-B1 | ELASTOMER COMPOSITIONS MODIFIED BY SILANES | DOW CORNING (US) | 2013-10-16 | — | — | EP | disclosed |
| US-20120059121-A1 | Elastomer Compositions Modified By Silanes | DOW CORNING EUROPE SA (BE) | 2012-03-08 | — | — | US | disclosed |
| US-20080199618-A1 | Using radiation curable acrylated polysiloxane solution with photoinitiator; waterproofing | ARKEMA INC. (US) | 2008-08-21 | — | — | US | disclosed |
| EP-1922154-A2 | METHOD OF STRENGTHENING A BRITTLE OXIDE SUBSTRATE WITH A WEATHERABLE COATING | Arkema Inc. (US) | 2008-05-21 | — | — | EP | disclosed |
| WO-2007008426-A2 | METHOD OF STRENGTHENING A BRITTLE OXIDE SUBSTRATE WITH A WEATHERABLE COATING | ARKEMA INC. (US) | 2007-01-18 | — | — | WO | disclosed |