Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNRHR | P30968 | 20/20 | 0.70 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13902208 | 0.93 | GNRHR (0.67) | GNRHR | |
| SCHEMBL778544 | 0.92 | GNRHR (0.83) | GNRHR | |
| SCHEMBL13722091 | 0.91 | GNRHR (0.76) | GNRHR | |
| SCHEMBL14747824 | 0.90 | GNRHR (0.71) | GNRHR | |
| SCHEMBL13722045 | 0.84 | GNRHR (0.79) | GNRHR | |
| SCHEMBL13722372 | 0.84 | GNRHR (0.85) | GNRHR | |
| SCHEMBL778069 | 0.83 | GNRHR (0.92) | GNRHR | |
| SCHEMBL779746 | 0.82 | GNRHR (1.00) | GNRHR | |
| SCHEMBL13721660 | 0.82 | GNRHR (0.74) | GNRHR | |
| SCHEMBL13721934 | 0.82 | GNRHR (0.73) | GNRHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090062258-A1 | FUSED PYRIMIDINE DERIVATIVE AND USE THEREOF | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-03-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090062258-A1 | FUSED PYRIMIDINE DERIVATIVE AND USE THEREOF | GNRHR, FSHR, NPY4R | GNRHR 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.