SCHEMBL13907710

SCHEMBL13907710

N=C(NCCCCc1ccc(OCC(O)C(O)O)cc1)NC(=O)c1nc(Cl)c(N)nc1N

nearest known ligand 0.57

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
SCNN1A P37088 20/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9913776 0.93 SCNN1A (0.60) SCNN1A
SCHEMBL14268266 0.93 SCNN1A (0.56) SCNN1A
SCHEMBL13375060 0.92 SCNN1A (0.58) SCNN1A
SCHEMBL12251731 0.92 SCNN1A (0.55) SCNN1A
SCHEMBL14551503 0.91 SCNN1A (0.57) SCNN1A
SCHEMBL9913771 0.91 SCNN1A (0.57) SCNN1A
552-02 Free Base SCHEMBL9913774 0.90 SCNN1A (0.71) SCNN1A
552-02 Free Base SCHEMBL2015162 0.90 SCNN1A (0.71) SCNN1A
SCHEMBL12120483 0.90 SCNN1A (0.61) SCNN1A
552-02 Free Base SCHEMBL9913757 0.90 SCNN1A (0.71) SCNN1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090062308-A1 METHODS OF USING SODIUM CHANNEL BLOCKERS PARION SCIENCES, INC. (US) 2009-03-05 US disclosed
US-20090062308-A1 METHODS OF USING SODIUM CHANNEL BLOCKERS PARION SCIENCES, INC. (US) 2009-03-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090062308-A1 METHODS OF USING SODIUM CHANNEL BLOCKERS SCN1B, KCNN3, SCN2B SCNN1A 30/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.