SCHEMBL13908239

SCHEMBL13908239

Cc1ccc(S(=O)(=O)N/N=C/c2cc(Br)c(C)cc2O)cc1

nearest known ligand 0.73

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 9/20 0.73
MAPT P10636 6/20 0.73
RBM39 Q14498 1/20 0.73
KMT2A Q03164 8/20 0.63
MEN1 O00255 7/20 0.63
POLB P06746 3/20 0.63
SMN1; SMN2 Q16637 2/20 0.59
ALOX12 P18054 1/20 0.57
HTT P42858 1/20 0.57
RRM1 P23921 1/20 0.52
LMNA P02545 1/20 0.51
TDP1 Q9NUW8 1/20 0.51
GAA P10253 3/20 0.50
RECQL P46063 1/20 0.49
L3MBTL1 Q9Y468 1/20 0.49
KDM4E B2RXH2 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13908087 0.90 KMT2A (0.62) ALDH1A1MAPTRBM39KMT2AMEN1
SCHEMBL13908083 0.86 ALDH1A1 (0.65) ALDH1A1MAPTRBM39KMT2AMEN1
SCHEMBL13908088 0.84 ALDH1A1 (0.81) ALDH1A1MAPTRBM39KMT2AMEN1
SCHEMBL13908082 0.84 ALDH1A1 (0.68) ALDH1A1MAPTRBM39KMT2AMEN1
SCHEMBL14027529 0.82 MAPT (0.67) ALDH1A1MAPTRBM39KMT2AMEN1
SCHEMBL10027945 0.82 ALDH1A1 (0.77) ALDH1A1MAPTRBM39KMT2AMEN1
SCHEMBL13908238 0.80 MAPT (0.56) ALDH1A1MAPTRBM39KMT2AMEN1
SCHEMBL27406135 0.80 MEN1 (0.64) ALDH1A1MAPTRBM39KMT2AMEN1
SCHEMBL29712245 0.80 MEN1 (0.64) ALDH1A1MAPTRBM39KMT2AMEN1
SCHEMBL13908086 0.80 ALDH1A1 (0.73) ALDH1A1MAPTRBM39KMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2009038879-A2 STEM CELL DIFFERENTIATING AGENTS AND USES THEREFOR THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) 2009-03-26 WO disclosed