Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VDR | P11473 | 4/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ALPG | P10696 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.33 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13908725 | 0.96 | VDR (0.32) | VDRMEN1NPC1S1PR4ALDH1A1 | |
| SCHEMBL13908694 | 0.77 | VDR (0.40) | VDRMEN1NPC1S1PR4ALDH1A1 | |
| SCHEMBL13908726 | 0.69 | PTGS1 (0.36) | VDRMEN1NPC1ALDH1A1LMNA | |
| SCHEMBL13908684 | 0.63 | SMN1; SMN2 (0.35) | MEN1ALDH1A1LMNAMAPTTHRB | |
| SCHEMBL13005151 | 0.63 | VDR (0.49) | VDRMEN1NPC1S1PR4ALDH1A1 | |
| SCHEMBL13763331 | 0.60 | MAPT (0.41) | MEN1NPC1ALDH1A1LMNAPOLB | |
| SCHEMBL11932973 | 0.60 | PTGER4 (0.36) | ALDH1A1LMNAPOLBMAPTPKM | |
| SCHEMBL13862424 | 0.60 | SRC (0.31) | POLBPKM | |
| SCHEMBL13908728 | 0.59 | PTGER4 (0.51) | MEN1ALDH1A1LMNAPOLBMAPT | |
| SCHEMBL13908683 | 0.59 | VDR (0.41) | VDRMEN1NPC1S1PR4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009037348-A1 | INDOLINIUM-DERIVED THIOL/DISULFIDE DYE, DYE COMPOSITION COMPRISNG THIS DYE, PROCESS FOR LIGHTENING KERATIN MATERIALS USING THIS DYE | L'OREAL (FR) | 2009-03-26 | — | — | WO | disclosed |