SCHEMBL13908970

SCHEMBL13908970

CCOCCC(C)CN(CC1CC1)c1c(SC)nn2c(I)cccc12

nearest known ligand 0.44

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
CRHR1 P34998 20/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13908987 0.80 CRHR1 (0.50) CRHR1
SCHEMBL4034427 0.76 CRHR1 (0.65) CRHR1
SCHEMBL5849088 0.67 CRHR1 (0.55) CRHR1
SCHEMBL13015898 0.67 CRHR1 (0.56) CRHR1
SCHEMBL3043494 0.65 CRHR1 (0.68) CRHR1
SCHEMBL1942753 0.64 CRHR1 (0.72) CRHR1
Hydrochloric Acid SCHEMBL3041431 0.64 CRHR1 (0.67) CRHR1
SCHEMBL1942151 0.64 CRHR1 (0.77) CRHR1
SCHEMBL1940402 0.64 CRHR1 (0.77) CRHR1
SCHEMBL1943303 0.64 CRHR1 (0.90) CRHR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1555265-B1 7-PHENYL PYRAZOLOPYRIDINE COMPOUNDS EISAI R&D MAN CO LTD (JP) 2009-03-25 EP disclosed