Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IKBKB | O14920 | 1/20 | 0.30 |
| ▸ | CHUK | O15111 | 1/20 | 0.30 |
| ▸ | LYN | P07948 | 1/20 | 0.30 |
| ▸ | IGF1R | P08069 | 1/20 | 0.30 |
| ▸ | SYK | P43405 | 1/20 | 0.30 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.30 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.30 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14850232 | 0.94 | LYN (0.32) | IKBKBCHUKLYNIGF1RSYK | |
| SCHEMBL14850208 | 0.92 | IKBKB (0.30) | IKBKBCHUKLYNIGF1RSYK | |
| SCHEMBL13751 | 0.92 | LYN (0.34) | IKBKBCHUKLYNIGF1RSYK | |
| SCHEMBL13780 | 0.91 | LYN (0.33) | IKBKBCHUKLYNIGF1RSYK | |
| SCHEMBL14850202 | 0.88 | HPSE (0.34) | IKBKBCHUKLYNIGF1RSYK | |
| SCHEMBL14124 | 0.88 | HPSE (0.34) | IKBKBCHUKLYNIGF1RSYK | |
| SCHEMBL17354372 | 0.88 | KDR (0.31) | IKBKBCHUKLYNIGF1RSYK | |
| SCHEMBL17354234 | 0.87 | — | — | |
| SCHEMBL13705 | 0.87 | GPR142 (0.33) | IKBKBCHUKLYNIGF1RSYK | |
| SCHEMBL13876 | 0.86 | JAK1 (0.31) | IKBKBCHUKLYNIGF1RSYK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011047323-A2 | ANTIMICROBIAL COMPOUNDS AND METHODS OF MAKING AND USING THE SAME | RIB-X PHARMACEUTICALS, INC. (US) | 2011-04-21 | — | — | WO | disclosed |