Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 10/20 | 0.63 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.42 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13910421 | 0.90 | GSK3B (0.64) | GSK3BMEN1KMT2AALDH1A1 | |
| SCHEMBL14063471 | 0.89 | GSK3B (0.71) | GSK3BCYP2D6 | |
| SCHEMBL13722002 | 0.88 | GSK3B (0.49) | GSK3BCYP1A2CYP2D6 | |
| SCHEMBL14063468 | 0.87 | GSK3B (0.75) | GSK3BKMT2AALDH1A1 | |
| SCHEMBL13910495 | 0.83 | GSK3B (0.71) | GSK3BMEN1KMT2AALDH1A1 | |
| SCHEMBL14063466 | 0.83 | GSK3B (0.80) | GSK3B | |
| SCHEMBL13910320 | 0.83 | GSK3B (0.71) | GSK3BCYP2D6 | |
| SCHEMBL13910423 | 0.82 | GSK3B (0.69) | GSK3B | |
| SCHEMBL13910834 | 0.81 | GSK3B (0.78) | GSK3B | |
| SCHEMBL14063465 | 0.81 | GSK3B (0.80) | GSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1427720-B1 | 3-SUBSTITUTED-4-PYRIMIDONE DERIVATIVES | MITSUBISHI TANABE PHARMA CORP (JP) | 2009-03-04 | — | — | EP | disclosed |