Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 7/20 | 0.50 |
| ▸ | TTR | P02766 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | CXCL8 | P10145 | 2/20 | 0.38 |
| ▸ | CLIC1 | O00299 | 1/20 | 0.38 |
| ▸ | CLCN2 | P51788 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.37 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.37 |
| ▸ | UGT1A9 | O60656 | 1/20 | 0.37 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.37 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.37 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.37 |
| ▸ | ALB | P02768 | 1/20 | 0.37 |
| ▸ | UGT1A6 | P19224 | 1/20 | 0.37 |
| ▸ | UGT1A1 | P22309 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13299190 | 0.84 | TTR (0.64) | PTGS2TTRCYP2C9USP2LMNA | |
| SCHEMBL27637959 | 0.81 | TTR (0.60) | PTGS2TTRCYP2C9USP2LMNA | |
| SCHEMBL25720185 | 0.76 | PTGS2 (0.57) | PTGS2TTRCYP2C9USP2LMNA | |
| SCHEMBL11567028 | 0.74 | PTGS2 (0.73) | PTGS2TTRCYP2C9USP2LMNA | |
| SCHEMBL11564032 | 0.71 | PTGS2 (0.61) | PTGS2TTRCYP2C9USP2LMNA | |
| SCHEMBL13911457 | 0.71 | TBXA2R (0.44) | PTGS2LMNATBXA2RKMT2AGAA | |
| SCHEMBL18878994 | 0.70 | TTR (0.67) | PTGS2TTRCYP2C9USP2LMNA | |
| SCHEMBL10844751 | 0.69 | TTR (0.70) | PTGS2TTRCYP2C9USP2LMNA | |
| SCHEMBL25719225 | 0.69 | PTGS2 (0.57) | PTGS2TTRCYP2C9USP2LMNA | |
| SCHEMBL13089839 | 0.69 | PTGS2 (0.60) | PTGS2TTRCYP2C9USP2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009037707-A2 | N-PHENYL ANTHRANILIC ACID DERIVATIVES AND USES THEREOF | RAMOT AT TEL AVIV UNIVERSITY LTD. (IL) | 2009-03-26 | — | — | WO | disclosed |