Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 4/20 | 0.64 |
| ▸ | TTR | P02766 | 3/20 | 0.64 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.64 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.64 |
| ▸ | UGT1A9 | O60656 | 1/20 | 0.64 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.64 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.64 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.64 |
| ▸ | ALB | P02768 | 1/20 | 0.64 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.64 |
| ▸ | UGT1A6 | P19224 | 1/20 | 0.64 |
| ▸ | UGT1A1 | P22309 | 1/20 | 0.64 |
| ▸ | CXCR1 | P25024 | 1/20 | 0.64 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.64 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.64 |
| ▸ | NR1I3 | Q14994 | 1/20 | 0.64 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.64 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.64 |
| ▸ | UGT1A7 | Q9HAW7 | 1/20 | 0.64 |
| ▸ | UGT1A10 | Q9HAW8 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25948151 | 0.88 | PTGS2 (0.63) | PTGS2TTRPTGS1AKR1B10UGT1A9 | |
| SCHEMBL13299169 | 0.88 | PTGS2 (0.66) | PTGS2TTRPTGS1AKR1B10UGT1A9 | |
| SCHEMBL18500866 | 0.87 | CA12 (0.62) | PTGS2TTRPTGS1AKR1B10UGT1A9 | |
| SCHEMBL15340508 | 0.85 | CA12 (0.64) | PTGS2TTRPTGS1AKR1B10UGT1A9 | |
| SCHEMBL12651566 | 0.84 | CA12 (0.65) | PTGS2TTRPTGS1AKR1B10UGT1A9 | |
| SCHEMBL10797057 | 0.84 | CA12 (0.65) | PTGS2TTRPTGS1AKR1B10UGT1A9 | |
| SCHEMBL577718 | 0.83 | PTGS2 (0.71) | PTGS2TTRPTGS1AKR1B10UGT1A9 | |
| SCHEMBL22846863 | 0.83 | PTGS2 (0.71) | PTGS2TTRPTGS1AKR1B10UGT1A9 | |
| SCHEMBL30465077 | 0.83 | PTGS2 (0.71) | PTGS2TTRPTGS1AKR1B10UGT1A9 | |
| SCHEMBL13653128 | 0.83 | PTGS2 (0.54) | PTGS2TTRPTGS1AKR1B10UGT1A9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009037707-A2 | N-PHENYL ANTHRANILIC ACID DERIVATIVES AND USES THEREOF | RAMOT AT TEL AVIV UNIVERSITY LTD. (IL) | 2009-03-26 | — | — | WO | disclosed |