Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSTP1 | P09211 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 9/20 | 0.41 |
| ▸ | MAOA | P21397 | 5/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 5/20 | 0.38 |
| ▸ | CA4 | P22748 | 5/20 | 0.38 |
| ▸ | CA9 | Q16790 | 5/20 | 0.38 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.35 |
| ▸ | MGAM | O43451 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3204571 | 0.84 | GSTP1 (0.52) | GSTP1MAOBMAOAACHECA12 | |
| SCHEMBL13185268 | 0.81 | MAOB (0.49) | GSTP1MAOBMAOACA12CA9 | |
| SCHEMBL20018470 | 0.79 | GSTP1 (0.42) | GSTP1MAOBMAOAACHECA12 | |
| SCHEMBL4284484 | 0.79 | GSTP1 (0.42) | GSTP1MAOBMAOAACHECA12 | |
| SCHEMBL4278916 | 0.79 | GSTP1 (0.46) | GSTP1MAOBMAOAACHECA12 | |
| SCHEMBL7381752 | 0.79 | CA12 (0.50) | GSTP1MAOBMAOAACHECA12 | |
| SCHEMBL13591057 | 0.79 | GSTP1 (0.42) | GSTP1MAOBMAOAACHECA12 | |
| SCHEMBL13592464 | 0.78 | MAOB (0.47) | GSTP1MAOBMAOAACHECA12 | |
| SCHEMBL31404220 | 0.78 | ALDH1A1 (0.50) | GSTP1MAOBMAOAACHECA12 | |
| SCHEMBL105466 | 0.75 | GSTP1 (0.46) | GSTP1MAOBMAOAACHECA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090069561-A1 | CLICK CHEMISTRY ROUTE TO TRIAZOLE DENDRIMERS | THE SCRIPPS RESEARCH INSTITUTE (US) | 2009-03-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090069561-A1 | CLICK CHEMISTRY ROUTE TO TRIAZOLE DENDRIMERS | CROCC, JAK3, APOBEC3A | GSTP1 3597/4885MAOB 2450/4885MAOA 3629/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.