Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.47 |
| ▸ | RAB9A | P51151 | 7/20 | 0.47 |
| ▸ | NPC1 | O15118 | 6/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13846399 | 0.92 | MAPT (0.51) | MAPTRAB9ANPC1MAPK1HPGD | |
| SCHEMBL13846398 | 0.82 | MAPT (0.52) | MAPTRAB9ANPC1MAPK1HPGD | |
| SCHEMBL13846397 | 0.79 | MAPT (0.60) | MAPTRAB9ANPC1MAPK1HPGD | |
| SCHEMBL13846411 | 0.76 | MAPT (0.74) | MAPTRAB9ANPC1MAPK1HPGD | |
| SCHEMBL15504784 | 0.75 | MAPT (0.46) | MAPTRAB9ANPC1MAPK1HPGD | |
| SCHEMBL13846407 | 0.75 | MAPT (0.55) | MAPTRAB9ANPC1MAPK1HPGD | |
| SCHEMBL13846410 | 0.75 | RAB9A (0.68) | MAPTRAB9ANPC1MAPK1HPGD | |
| SCHEMBL13849752 | 0.75 | MAPT (0.61) | MAPTRAB9ANPC1MAPK1HPGD | |
| SCHEMBL15504786 | 0.75 | MAPT (0.58) | MAPTRAB9ANPC1MAPK1HPGD | |
| SCHEMBL13846403 | 0.74 | MAPT (0.58) | MAPTRAB9ANPC1MAPK1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2039677-A1 | ORGANIC COMPOUNDS CONTAINING HETEROATOMS AND THEIR USE IN ZIEGLER-NATTA CATALYST WITH SINGLE ACTIVATION CENTER | SHANGHAI INSTITUTE OF ORGANIC CHEMISTRY, CHINESE ACADEMY OF SCIENCES (CN) | 2009-03-25 | — | — | EP | disclosed |