SCHEMBL13918366

SCHEMBL13918366

CCCCCCCCOc1ccc(CCCOc2ccc(C(=O)OC)cc2C(=O)NC2CCCC(C(=O)OC)C2)cc1

nearest known ligand 0.67

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
CYSLTR2 Q9NS75 2/20 0.67
CNR2 P34972 5/20 0.42
MDH1 P40925 1/20 0.40
THRA P10827 1/20 0.40
THRB P10828 1/20 0.40
CNR1 P21554 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13918361 1.00 CYSLTR2 (0.67) CYSLTR2CNR2MDH1THRATHRB
SCHEMBL13918369 1.00 CYSLTR2 (0.67) CYSLTR2CNR2MDH1THRATHRB
SCHEMBL13918313 0.93 CYSLTR2 (0.61) CYSLTR2CNR2MDH1CNR1
SCHEMBL4521894 0.93 CYSLTR2 (0.78) CYSLTR2
SCHEMBL4522542 0.92 CYSLTR2 (0.63) CYSLTR2CNR2
SCHEMBL4524350 0.92 CYSLTR2 (0.74) CYSLTR2
SCHEMBL13918306 0.91 CYSLTR2 (0.61) CYSLTR2CNR2MDH1
SCHEMBL13932995 0.91 CYSLTR2 (0.75) CYSLTR2
SCHEMBL4522056 0.91 CYSLTR2 (0.65) CYSLTR2
SCHEMBL4530062 0.90 CYSLTR2 (0.78) CYSLTR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7498460-B2 Isophthalic acid derivatives BAYER HEALTHCARE AG (DE) 2009-03-03 US disclosed
US-7498460-B2 Isophthalic acid derivatives BAYER HEALTHCARE AG (DE) 2009-03-03 US disclosed