Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR2 | Q9NS75 | 2/20 | 0.55 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.43 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | MMP2 | P08253 | 1/20 | 0.42 |
| ▸ | MMP3 | P08254 | 1/20 | 0.42 |
| ▸ | MMP10 | P09238 | 1/20 | 0.42 |
| ▸ | MMP8 | P22894 | 1/20 | 0.42 |
| ▸ | MMP12 | P39900 | 1/20 | 0.42 |
| ▸ | MMP13 | P45452 | 1/20 | 0.42 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.40 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.39 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13918435 | 0.93 | CYSLTR2 (0.48) | CYSLTR2CYP4F2CYP4A11L3MBTL1MMP2 | |
| SCHEMBL4532981 | 0.91 | CYSLTR2 (0.55) | CYSLTR2PLA2G4BS1PR1FFAR1CYSLTR1 | |
| SCHEMBL4516413 | 0.90 | CYSLTR2 (0.56) | CYSLTR2CYP4F2CYP4A11PLA2G4BS1PR1 | |
| SCHEMBL13918523 | 0.88 | CYSLTR2 (0.65) | CYSLTR2CYP4F2CYP4A11PLA2G4BSCN9A | |
| SCHEMBL4508597 | 0.86 | CYSLTR2 (0.49) | CYSLTR2MEN1KMT2A | |
| SCHEMBL6199651 | 0.86 | CYSLTR2 (0.59) | CYSLTR2PLA2G4BSCN9AMEN1NPC1 | |
| SCHEMBL13918480 | 0.86 | CYSLTR2 (0.46) | CYSLTR2L3MBTL1SCN9AMEN1NPC1 | |
| SCHEMBL13918375 | 0.84 | CYSLTR2 (0.60) | CYSLTR2PLA2G4BMEN1MAPTKMT2A | |
| SCHEMBL4522253 | 0.82 | CYSLTR2 (0.64) | CYSLTR2PLA2G4BS1PR1NPC1ALDH1A1 | |
| SCHEMBL4526773 | 0.82 | CYSLTR2 (0.64) | CYSLTR2PLA2G4BS1PR1FFAR1CYSLTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7498460-B2 | Isophthalic acid derivatives | BAYER HEALTHCARE AG (DE) | 2009-03-03 | — | — | US | disclosed |
| US-7498460-B2 | Isophthalic acid derivatives | BAYER HEALTHCARE AG (DE) | 2009-03-03 | — | — | US | disclosed |