Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR2 | Q9NS75 | 2/20 | 0.64 |
| ▸ | S1PR1 | P21453 | 11/20 | 0.48 |
| ▸ | S1PR3 | Q99500 | 7/20 | 0.48 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.45 |
| ▸ | S1PR5 | Q9H228 | 5/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | CASP6 | P55212 | 1/20 | 0.43 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.43 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.42 |
| ▸ | PDE4A | P27815 | 1/20 | 0.41 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.41 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13918523 | 0.91 | CYSLTR2 (0.65) | CYSLTR2S1PR1S1PR3PLA2G4BS1PR5 | |
| SCHEMBL4522253 | 0.90 | CYSLTR2 (0.64) | CYSLTR2S1PR1S1PR3PLA2G4BS1PR5 | |
| SCHEMBL4532981 | 0.89 | CYSLTR2 (0.55) | CYSLTR2S1PR1S1PR3PLA2G4BS1PR5 | |
| SCHEMBL13918454 | 0.89 | CYSLTR2 (0.62) | CYSLTR2S1PR1S1PR3PLA2G4BS1PR5 | |
| SCHEMBL5207067 | 0.89 | CYSLTR2 (0.55) | CYSLTR2S1PR1S1PR3PLA2G4BPOLB | |
| SCHEMBL13918475 | 0.88 | CYSLTR2 (0.61) | CYSLTR2S1PR1S1PR3PLA2G4BS1PR5 | |
| SCHEMBL6199651 | 0.87 | CYSLTR2 (0.59) | CYSLTR2PLA2G4BPOLBCASP6NR1H4 | |
| SCHEMBL13918337 | 0.87 | CYSLTR2 (0.60) | CYSLTR2S1PR1S1PR3PLA2G4BS1PR5 | |
| SCHEMBL13918478 | 0.85 | CYSLTR2 (0.57) | CYSLTR2S1PR1S1PR3PLA2G4BS1PR5 | |
| SCHEMBL13918389 | 0.83 | CYSLTR2 (0.56) | CYSLTR2S1PR1S1PR3PLA2G4BS1PR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7498460-B2 | Isophthalic acid derivatives | BAYER HEALTHCARE AG (DE) | 2009-03-03 | — | — | US | disclosed |
| US-7498460-B2 | Isophthalic acid derivatives | BAYER HEALTHCARE AG (DE) | 2009-03-03 | — | — | US | disclosed |
| US-7498460-B2 | Isophthalic acid derivatives | BAYER HEALTHCARE AG (DE) | 2009-03-03 | — | — | US | disclosed |
| EP-1572628-B1 | ISOPHTALIC ACID DERIVATIVES | BAYER HEALTHCARE AG (DE) | 2007-07-25 | — | — | EP | disclosed |
| EP-1572628-B1 | ISOPHTALIC ACID DERIVATIVES | BAYER HEALTHCARE AG (DE) | 2007-07-25 | — | — | EP | disclosed |
| US-20060154912-A1 | Isophtalic acid derivatives | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2006-07-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060154912-A1 | Isophtalic acid derivatives | VHL, FABP3, CPT1A | CYSLTR2 1426/4885S1PR1 4458/4885S1PR3 4374/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.