Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | F10 | P00742 | 18/20 | 0.40 |
| ▸ | KLK1 | P06870 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2472222 | 0.92 | F10 (0.42) | KCNH2F10KLK1 | |
| SCHEMBL13920007 | 0.87 | KCNH2 (0.40) | KCNH2F10KLK1KMT2A | |
| SCHEMBL4524008 | 0.86 | F10 (0.42) | KCNH2F10KLK1 | |
| SCHEMBL15489311 | 0.86 | F10 (0.34) | KCNH2F10 | |
| SCHEMBL4516582 | 0.86 | KCNH2 (0.40) | KCNH2F10KLK1 | |
| SCHEMBL4532098 | 0.86 | F10 (0.41) | KCNH2F10KLK1KMT2A | |
| SCHEMBL4528388 | 0.86 | F10 (0.42) | KCNH2F10KLK1 | |
| SCHEMBL4524733 | 0.85 | F10 (0.43) | KCNH2F10KLK1 | |
| SCHEMBL4530729 | 0.83 | F10 (0.45) | KCNH2F10KLK1 | |
| SCHEMBL4525032 | 0.81 | F10 (0.40) | KCNH2F10KLK1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090076015-A1 | Tricyclic Spiro Compound Comprising Acyl Group Bound to Nitrogen Atom in the Ring | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2009-03-19 | — | — | US | disclosed |
| US-20090076015-A1 | Tricyclic Spiro Compound Comprising Acyl Group Bound to Nitrogen Atom in the Ring | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2009-03-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090076015-A1 | Tricyclic Spiro Compound Comprising Acyl Group Bound to Nitrogen Atom in the Ring | KCNH1, SCN1A, SCN10A | KCNH2 25/4885F10 157/4885KLK1 1032/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.