Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 6/20 | 0.35 |
| ▸ | DPP8 | Q6V1X1 | 6/20 | 0.35 |
| ▸ | DPP9 | Q86TI2 | 6/20 | 0.35 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.33 |
| ▸ | FAP | Q12884 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16376157 | 0.82 | ALDH1A1 (0.46) | ATMALDH1A1 | |
| SCHEMBL13661911 | 0.82 | ALDH1A1 (0.46) | ATMALDH1A1 | |
| SCHEMBL2608451 | 0.82 | ALDH1A1 (0.46) | ATMALDH1A1 | |
| SCHEMBL18084393 | 0.82 | ALDH1A1 (0.46) | ATMALDH1A1 | |
| SCHEMBL2610758 | 0.82 | ALDH1A1 (0.46) | ATMALDH1A1 | |
| SCHEMBL13920579 | 0.78 | KMT2A (0.34) | ATMALDH1A1 | |
| SCHEMBL15760363 | 0.76 | ATM (0.43) | DPP4DPP8DPP9DPP7FAP | |
| SCHEMBL7806430 | 0.76 | ATM (0.52) | DPP4DPP8DPP9DPP7FAP | |
| SCHEMBL85622 | 0.76 | ATM (0.52) | DPP4DPP8DPP9DPP7FAP | |
| SCHEMBL12795649 | 0.76 | ATM (0.52) | DPP4DPP8DPP9DPP7FAP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7511062-B2 | Substituted 2-quinolyl-oxazoles useful as PDE4 inhibitors | SCHERING CORPORATION (US) | 2009-03-31 | — | — | US | disclosed |