Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 18/20 | 0.80 |
| ▸ | MAPK13 | O15264 | 5/20 | 0.71 |
| ▸ | MAPK12 | P53778 | 5/20 | 0.71 |
| ▸ | MAPK11 | Q15759 | 5/20 | 0.71 |
| ▸ | DDR2 | Q16832 | 4/20 | 0.70 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.70 |
| ▸ | SRC | P12931 | 1/20 | 0.68 |
| ▸ | RAF1 | P04049 | 1/20 | 0.59 |
| ▸ | BRAF | P15056 | 1/20 | 0.59 |
| ▸ | EPHB2 | P29323 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4303670 | 0.91 | MAPK14 (0.86) | MAPK14MAPK13MAPK12MAPK11DDR2 | |
| SCHEMBL3185693 | 0.89 | MAPK14 (1.00) | MAPK14MAPK13MAPK12MAPK11DDR2 | |
| SCHEMBL2082430 | 0.87 | MAPK14 (0.82) | MAPK14MAPK13MAPK12MAPK11DDR2 | |
| SCHEMBL2616997 | 0.87 | MAPK14 (0.82) | MAPK14MAPK13MAPK12MAPK11DDR2 | |
| SCHEMBL2085734 | 0.86 | MAPK14 (0.86) | MAPK14MAPK13MAPK12MAPK11DDR2 | |
| SCHEMBL3294236 | 0.85 | MAPK14 (0.77) | MAPK14MAPK13MAPK12MAPK11DDR2 | |
| SCHEMBL4263729 | 0.85 | MAPK14 (0.81) | MAPK14MAPK13MAPK12MAPK11DDR2 | |
| SCHEMBL2081374 | 0.85 | MAPK14 (0.84) | MAPK14MAPK13MAPK12MAPK11DDR2 | |
| SCHEMBL2081795 | 0.85 | MAPK14 (0.79) | MAPK14MAPK13MAPK12MAPK11DDR2 | |
| SCHEMBL3294796 | 0.85 | MAPK14 (0.75) | MAPK14MAPK13MAPK12MAPK11DDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8802053-B2 | Radio-methyl vorozole and methods for making and using the same | BROOKHAVEN SCIENCE ASSOCIATES, LLC (US) | 2014-08-12 | — | — | US | disclosed |