SCHEMBL3185693

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4303670	0.92	MAPK14 (0.86)	MAPK14DDR2SRCMAPK9RAF1
	SCHEMBL13857351	0.92	MAPK14 (0.85)	MAPK14DDR2SRCMAPK9RAF1
	SCHEMBL2085734	0.91	MAPK14 (0.86)	MAPK14DDR2SRCMAPK9RAF1
	SCHEMBL2082430	0.90	MAPK14 (0.82)	MAPK14DDR2SRCMAPK9MAPK13
	SCHEMBL2616997	0.90	MAPK14 (0.82)	MAPK14DDR2SRCMAPK9MAPK13
	SCHEMBL2083986	0.90	MAPK14 (1.00)	MAPK14DDR2SRCMAPK9RAF1
	SCHEMBL13923906	0.89	MAPK14 (0.80)	MAPK14DDR2SRCMAPK9RAF1
	SCHEMBL2083238	0.89	MAPK14 (0.80)	MAPK14DDR2SRCMAPK9RAF1
	SCHEMBL2081374	0.89	MAPK14 (0.84)	MAPK14DDR2SRCMAPK9MAPK13
	SCHEMBL2081795	0.88	MAPK14 (0.79)	MAPK14DDR2SRCMAPK9RAF1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 71 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.