Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4A | O75164 | 2/20 | 0.68 |
| ▸ | KDM2A | Q9Y2K7 | 2/20 | 0.68 |
| ▸ | HTT | P42858 | 4/20 | 0.58 |
| ▸ | MEN1 | O00255 | 3/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.58 |
| ▸ | MAPT | P10636 | 2/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.58 |
| ▸ | APAF1 | O14727 | 2/20 | 0.58 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.58 |
| ▸ | BLM | P54132 | 1/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.58 |
| ▸ | CHAT | P28329 | 1/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8080488 | 1.00 | KDM4A (0.68) | KDM4AKDM2AHTTMEN1KMT2A | |
| SCHEMBL13046320 | 1.00 | KDM4A (0.68) | KDM4AKDM2AHTTMEN1KMT2A | |
| SCHEMBL8080485 | 1.00 | KDM4A (0.68) | KDM4AKDM2AHTTMEN1KMT2A | |
| Bromide SCHEMBL1594965 | 0.98 | KDM4A (0.66) | KDM4AKDM2AHTTMEN1KMT2A | |
| Bromide SCHEMBL1594966 | 0.98 | KDM4A (0.66) | KDM4AKDM2AHTTMEN1KMT2A | |
| SCHEMBL13924728 | 0.91 | KDM4A (0.58) | KDM4AKDM2AHTTMEN1KMT2A | |
| SCHEMBL13924753 | 0.88 | KDM4A (0.55) | KDM4AKDM2AHTTMEN1KMT2A | |
| SCHEMBL13924727 | 0.86 | KDM4A (0.49) | KDM4AKDM2AHTTMEN1KMT2A | |
| SCHEMBL13698933 | 0.85 | KDM4A (0.49) | KDM4AKDM2AHTTMEN1KMT2A | |
| SCHEMBL9453337 | 0.84 | KMT2A (0.69) | HTTMEN1KMT2AMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7488354-B2 | Dyeing composition comprising at least one disulphide dye and method of dyeing human keratin fibers using this dye | L'OREAL S.A. (FR) | 2009-02-10 | — | — | US | disclosed |