Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.42 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.37 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | CPB2 | Q96IY4 | 3/20 | 0.33 |
| ▸ | CPB1 | P15086 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL151394 | 0.74 | SMYD3 (0.50) | SMYD3MAP3K5CYP2E1CYP3A4CYP2A6 | |
| SCHEMBL6335415 | 0.73 | SMYD3 (0.52) | SMYD3MAP3K5CYP2E1CYP3A4CYP2A6 | |
| SCHEMBL16566390 | 0.70 | SMYD3 (0.57) | SMYD3MAP3K5CYP2E1CYP3A4CYP2A6 | |
| SCHEMBL7425205 | 0.70 | SMYD3 (0.50) | SMYD3MAP3K5CYP2E1CYP3A4CYP2A6 | |
| SCHEMBL25153647 | 0.69 | NOTUM (0.51) | SMYD3MAP3K5 | |
| SCHEMBL27550007 | 0.69 | SMYD3 (0.46) | SMYD3MAP3K5CYP2E1CYP3A4CYP2A6 | |
| SCHEMBL28195819 | 0.69 | — | — | |
| SCHEMBL30162870 | 0.67 | SMYD3 (0.57) | SMYD3MAP3K5CPB2 | |
| SCHEMBL3955613 | 0.64 | — | — | |
| SCHEMBL9031994 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7491818-B2 | Nucleic acid labeling compounds | AFFYMETRIX, INC. (US) | 2009-02-17 | — | — | US | disclosed |