Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.50 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.45 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.44 |
| ▸ | CPB2 | Q96IY4 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.41 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | CPB1 | P15086 | 1/20 | 0.39 |
| ▸ | KDM5A | P29375 | 1/20 | 0.39 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.39 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL710279 | 0.85 | KDM5A (0.54) | SMYD3PLA2G4ACPB2KDM4ECYP3A4 | |
| SCHEMBL12159797 | 0.84 | SMYD3 (0.50) | SMYD3PLA2G4AMAP3K5CPB2CYP3A4 | |
| SCHEMBL6335415 | 0.82 | SMYD3 (0.52) | SMYD3MAP3K5CPB2KDM4ECYP3A4 | |
| SCHEMBL2283649 | 0.82 | PLA2G4A (0.50) | SMYD3PLA2G4ACPB2KDM4ECYP3A4 | |
| SCHEMBL3689829 | 0.82 | PLA2G4A (0.40) | SMYD3PLA2G4AKDM4EKDM5AKDM5B | |
| SCHEMBL30268827 | 0.80 | PLA2G4A (0.52) | SMYD3PLA2G4ACPB2KDM4ECYP3A4 | |
| SCHEMBL14152089 | 0.80 | PLA2G4A (0.43) | SMYD3PLA2G4ACPB2KDM4ECPB1 | |
| SCHEMBL4590582 | 0.80 | PLA2G4A (0.42) | SMYD3PLA2G4AKDM4EKDM5AKDM5B | |
| SCHEMBL4901656 | 0.80 | PLA2G4A (0.39) | SMYD3PLA2G4AKDM4EKDM5AKDM5B | |
| SCHEMBL3690823 | 0.80 | PLA2G4A (0.39) | SMYD3PLA2G4AKDM4EKDM5AKDM5B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11668708-B2 | Method for reducing measurement error in latex agglutination immunoassay | SEKISUI MEDICAL CO., LTD. (JP) | 2023-06-06 | — | — | US | claimed |
| EP-1869019-B1 | BICYCLIC [3.1.0] HETEROARYL AMIDES AS TYPE I GLYCINE TRANSPORT INHIBITORS | PFIZER PROD INC (US) | 2014-08-27 | — | — | EP | claimed |
| US-20250214984-A1 | COMPOUND HAVING KDM5 INHIBITORY ACTIVITY AND PHARMACEUTICAL USE THEREOF | ONO PHARMACEUTICAL CO., LTD. (JP) | 2025-07-03 | — | — | US | disclosed |
| EP-4146645-B1 | 3-AZABICYCLO(3.1.0)HEXANE DERIVATIVES HAVING KDM5 INHIBITORY ACTIVITY AND USE THEREOF | ONO PHARMACEUTICAL CO (JP) | 2025-06-25 | — | — | EP | disclosed |
| US-12269817-B2 | Compound having KDM5 inhibitory activity and pharmaceutical use thereof | ONO PHARMACEUTICAL CO., LTD. (JP) | 2025-04-08 | — | — | US | disclosed |
| EP-4471027-A1 | 3-AZABICYCLO(3.1.0)HEXANE DERIVATIVES HAVING KDM5 INHIBITORY ACTIVITY AND USE THEREOF | ONO Pharmaceutical Co., Ltd. (JP) | 2024-12-04 | — | — | EP | disclosed |
| CN-116283920-B | 2, 4-disubstituted pyridine compound and application thereof | 贵州医科大学 | 2024-04-16 | — | — | CN | disclosed |
| CN-115461338-B | 3-azabicyclo (3.1.0) hexane derivatives having KDM5 inhibitory activity and uses thereof | 小野药品工业株式会社 | 2024-02-20 | — | — | CN | disclosed |
| US-20230271952-A1 | COMPOUND HAVING KDM5 INHIBITORY ACTIVITY AND PHARMACEUTICAL USE THEREOF | ONO PHARMACEUTICAL CO., LTD. (JP) | 2023-08-31 | — | — | US | disclosed |
| US-11691968-B2 | Compound having KDM5 inhibitory activity and pharmaceutical use thereof | ONO PHARMACEUTICAL CO., LTD. (JP) | 2023-07-04 | — | — | US | disclosed |
| CN-116283920-A | 2, 4-disubstituted pyridine compound and application thereof | 贵州医科大学 | 2023-06-23 | — | — | CN | disclosed |
| US-20100097743-A1 | CONDUCTIVE COMPOSITION VAND CONDUCTIVE CROSS-LINKED PRODUCT, CAPACITOR AND PRODUCTION METHOD THEREOF, AND ANTISTATIC COATING MATERIAL, ANTISTATIC COATING, ANTISTATIC FILM, OPTICAL FILTER, AND OPTICAL INFORMATION RECORDING MEDIUM | SHIN-ETSU POLYMER CO., LTD. (JP) | 2010-04-22 | — | — | US | disclosed |
| US-20100098841-A1 | CONDUCTIVE COMPOSITION VAND CONDUCTIVE CROSS-LINKED PRODUCT, CAPACITOR AND PRODUCTION METHOD THEREOF, AND ANTISTATIC COATING MATERIAL, ANTISTATIC COATING, ANTISTATIC FILM, OPTICAL FILTER, AND OPTICAL INFORMATION RECORDING MEDIUM | SHIN-ETSU POLYMER CO., LTD. (JP) | 2010-04-22 | — | — | US | disclosed |
| US-7666326-B2 | Conductive composition and conductive cross-linked product, capacitor and production method thereof, and antistatic coating material, antistatic coating, antistatic film, optical filter, and optical information recording medium | SHIN-ETSU POLYMER CO., LTD. (JP) | 2010-02-23 | — | — | US | disclosed |
| US-20060047030-A1 | Conductive composition and conductive cross-linked product, capacitor and production method thereof, and antistatic coating material, antistatic coating, antistatic film, optical filter, and optical information recording medium | SHIN-ETSU POLYMER CO., LTD | 2006-03-02 | — | — | US | disclosed |
| US-6579886-B2 | Ionotropic glutamate receptors; 6-((4-carboxylic acid-1H-imidazol-1-yl)methyl)-1,2,3,4,4a,5,6,7,8,8a-decahydroisoquinoline-3 -carboxylic acid | ELI LILLY AND COMPANY | 2003-06-17 | — | — | US | disclosed |
| US-20030055081-A1 | Selective iglur5 receptor antagonists | ELI LILLY AND COMPANY | 2003-03-20 | — | — | US | disclosed |
| EP-1257545-A1 | SELECTIVE iGLUR 5? RECEPTOR ANTAGONISTS | ELI LILLY AND COMPANY (US) | 2002-11-20 | — | — | EP | disclosed |
| WO-2001046173-A1 | SELECTIVE iGLUR5 RECEPTOR ANTAGONISTS | ELI LILLY AND COMPANY (US) | 2001-06-28 | — | — | WO | disclosed |
| US-5318975-A | 5-pyrimdineamine derivatives | BERLEX LABORATORIES, INC. (US) | 1994-06-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12269817-B2 | Compound having KDM5 inhibitory activity and pharmaceutical use thereof | KDM5A, KDM5B, KDM5D | SMYD3 49/4885PLA2G4A 3408/4885MAP3K5 289/4885 |
| US-20030055081-A1 | Selective iglur5 receptor antagonists | GRM5, GRIK5, GPR35 | SMYD3 1006/4885PLA2G4A 1720/4885MAP3K5 3215/4885 |
| US-11691968-B2 | Compound having KDM5 inhibitory activity and pharmaceutical use thereof | KDM5A, KDM5B, KDM5D | SMYD3 49/4885PLA2G4A 3408/4885MAP3K5 289/4885 |
| US-20250214984-A1 | COMPOUND HAVING KDM5 INHIBITORY ACTIVITY AND PHARMACEUTICAL USE THEREOF | KDM5A, KDM5B, KDM5D | SMYD3 49/4885PLA2G4A 3408/4885MAP3K5 289/4885 |
| US-20230271952-A1 | COMPOUND HAVING KDM5 INHIBITORY ACTIVITY AND PHARMACEUTICAL USE THEREOF | KDM5A, KDM5B, KDM5D | SMYD3 49/4885PLA2G4A 3408/4885MAP3K5 289/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.