Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 2/20 | 0.48 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | TGM2 | P21980 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.36 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.36 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27284572 | 0.82 | KCNA3 (0.46) | GRM2KCNA3KDM4ETGM2ALDH1A1 | |
| SCHEMBL3266560 | 0.79 | GRM2 (0.42) | GRM2KCNA3SMYD3 | |
| SCHEMBL24253400 | 0.78 | KCNA3 (0.41) | GRM2KCNA3TSHRSMYD3ACKR3 | |
| SCHEMBL1662858 | 0.77 | BAZ2B (0.46) | GRM2KCNA3SMYD3ACKR3 | |
| SCHEMBL20001503 | 0.75 | QPCT (0.41) | GRM2KCNA3SMYD3 | |
| SCHEMBL12911102 | 0.75 | P2RX7 (0.42) | GRM2KCNA3KDM4ETSHRSMYD3 | |
| SCHEMBL22231667 | 0.75 | KCNA3 (0.39) | GRM2KCNA3SMYD3ACKR3 | |
| SCHEMBL17511038 | 0.73 | HIF1A (0.65) | SMN1; SMN2ALDH1A1HDAC3HDAC1HDAC2 | |
| SCHEMBL19440870 | 0.72 | KCNA3 (0.47) | GRM2KCNA3SMN1; SMN2HDAC3HDAC4 | |
| SCHEMBL17518681 | 0.72 | GSK3B (0.42) | GRM2KCNA3SMYD3ACKR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7491818-B2 | Nucleic acid labeling compounds | AFFYMETRIX, INC. (US) | 2009-02-17 | — | — | US | disclosed |
| US-7423143-B2 | Nucleic acid labeling compounds | AFFYMETRIX. INC. (US) | 2008-09-09 | — | — | US | disclosed |
| US-7291463-B2 | Incubating/condensating pseudoisocytidine molecule with (1-(3-dimethylaminopropyl)-3-ethylcarbodiimide hydrochloride to provide a pseudouridine molecule; oncology diagnosis | AFFYMETRIX, INC. (US) | 2007-11-06 | — | — | US | disclosed |
| US-7179905-B2 | Nucleic acid labeling compounds | AFFYMETRIX, INC. (US) | 2007-02-20 | — | — | US | disclosed |