SCHEMBL13927745

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4137689	0.91	AURKA (0.45)	LMNAMAPTMEN1KMT2AKDM4E
	SCHEMBL4137691	0.91	AURKA (0.45)	LMNAMAPTMEN1KMT2AKDM4E
	SCHEMBL4136172	0.89	NPC1 (0.38)	LMNAMAPTMEN1KMT2ANPSR1
	SCHEMBL4136174	0.89	NPC1 (0.38)	LMNAMAPTMEN1KMT2ANPSR1
	SCHEMBL4141139	0.89	ALDH1A1 (0.37)	LMNAMAPTMEN1KMT2ACYP1A2
	SCHEMBL4141145	0.89	ALDH1A1 (0.37)	LMNAMAPTMEN1KMT2ACYP1A2
	SCHEMBL4144877	0.89	SMN1; SMN2 (0.41)	MAPTNPSR1KDM4EHPGDALDH1A1
	SCHEMBL4144873	0.89	SMN1; SMN2 (0.41)	MAPTNPSR1KDM4EHPGDALDH1A1
	SCHEMBL4146502	0.88	ALDH1A1 (0.37)	LMNAMAPTMEN1KMT2ANPSR1
	SCHEMBL4146508	0.88	ALDH1A1 (0.37)	LMNAMAPTMEN1KMT2ANPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.