Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.74 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.74 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.66 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.66 |
| ▸ | CHRM3 | P20309 | 12/20 | 0.63 |
| ▸ | CHRM1 | P11229 | 4/20 | 0.56 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.56 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.56 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.50 |
| ▸ | MLNR | O43193 | 1/20 | 0.50 |
| ▸ | HTR2A | P28223 | 1/20 | 0.50 |
| ▸ | HTR2C | P28335 | 1/20 | 0.50 |
| ▸ | HRH1 | P35367 | 1/20 | 0.50 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.50 |
| ▸ | DRD3 | P35462 | 1/20 | 0.50 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.50 |
| ▸ | HTR2B | P41595 | 1/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.50 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13928641 | 1.00 | ALDH1A1 (0.74) | ALDH1A1CYP1A2CYP3A4CYP2D6CHRM3 | |
| SCHEMBL10098830 | 1.00 | ALDH1A1 (0.74) | ALDH1A1CYP1A2CYP3A4CYP2D6CHRM3 | |
| SCHEMBL13928645 | 1.00 | ALDH1A1 (0.74) | ALDH1A1CYP1A2CYP3A4CYP2D6CHRM3 | |
| SCHEMBL13928644 | 1.00 | ALDH1A1 (0.74) | ALDH1A1CYP1A2CYP3A4CYP2D6CHRM3 | |
| SCHEMBL20355839 | 1.00 | ALDH1A1 (0.74) | ALDH1A1CYP1A2CYP3A4CYP2D6CHRM3 | |
| SCHEMBL13928647 | 0.94 | CYP2D6 (0.75) | ALDH1A1CYP1A2CYP3A4CYP2D6CHRM3 | |
| SCHEMBL13928650 | 0.94 | CYP2D6 (0.75) | ALDH1A1CYP1A2CYP3A4CYP2D6CHRM3 | |
| SCHEMBL13701451 | 0.93 | CHRM3 (0.70) | ALDH1A1CYP1A2CYP3A4CYP2D6CHRM3 | |
| SCHEMBL4245324 | 0.93 | CHRM3 (0.70) | ALDH1A1CYP1A2CYP3A4CYP2D6CHRM3 | |
| SCHEMBL13701453 | 0.93 | CHRM3 (0.70) | ALDH1A1CYP1A2CYP3A4CYP2D6CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090042942-A1 | Muscarinic Receptor Antagonists | ASTRAZENECA AB (SE) | 2009-02-12 | — | — | US | disclosed |
| US-20090042942-A1 | Muscarinic Receptor Antagonists | ASTRAZENECA AB (SE) | 2009-02-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090042942-A1 | Muscarinic Receptor Antagonists | CHRM2, CHRM3, CHRM1 | ALDH1A1 2300/4885CYP1A2 490/4885CYP3A4 522/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.