Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.44 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | UBE2N | P61088 | 1/20 | 0.41 |
| ▸ | RAD52 | P43351 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4205213 | 0.91 | POLB (0.40) | SMN1; SMN2KMT2AMEN1TDP1CYP2D6 | |
| SCHEMBL4205168 | 0.90 | ALDH1A1 (0.45) | KMT2AMEN1CYP2D6CYP3A4POLB | |
| SCHEMBL4212200 | 0.90 | KCNA5 (0.46) | SMN1; SMN2KMT2AMEN1CYP2C19CYP3A4 | |
| SCHEMBL4358102 | 0.90 | DRD4 (0.49) | SMN1; SMN2CYP2D6CYP2C19POLBALDH1A1 | |
| SCHEMBL4212892 | 0.88 | ALDH1A1 (0.39) | SMN1; SMN2KMT2AMEN1POLBALDH1A1 | |
| SCHEMBL4212566 | 0.87 | RAD52 (0.38) | SMN1; SMN2KMT2AMEN1TDP1CYP2D6 | |
| SCHEMBL4202948 | 0.86 | MEN1 (0.38) | SMN1; SMN2KMT2AMEN1POLBALDH1A1 | |
| SCHEMBL13928732 | 0.85 | SMN1; SMN2 (0.44) | SMN1; SMN2KMT2AMEN1TDP1CYP2D6 | |
| SCHEMBL13928735 | 0.84 | POLB (0.42) | SMN1; SMN2KMT2AMEN1TDP1CYP2C19 | |
| SCHEMBL4218431 | 0.84 | POLB (0.47) | SMN1; SMN2KMT2AMEN1POLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7488738-B2 | Aminophenoxyacetic acid derivatives and pharmaceutical composition containing thereof | ASUBIO PHARMA CO., LTD. (JP) | 2009-02-10 | — | — | US | disclosed |