Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | CCR5 | P51681 | 9/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4218435 | 0.88 | POLB (0.46) | POLBCCR5KDM4EALDH1A1 | |
| SCHEMBL4208779 | 0.86 | POLB (0.44) | POLBCCR5MEN1KMT2ANPC1 | |
| SCHEMBL4212217 | 0.85 | POLB (0.44) | POLBCCR5MEN1KMT2ANPC1 | |
| SCHEMBL4218431 | 0.82 | POLB (0.47) | POLBCCR5MEN1KMT2ANPC1 | |
| SCHEMBL4204989 | 0.82 | OPRM1 (0.49) | POLBSIGMAR1 | |
| SCHEMBL4208778 | 0.81 | POLB (0.46) | POLBCCR5KDM4EMEN1KMT2A | |
| SCHEMBL13928734 | 0.81 | POLB (0.46) | POLBCCR5KDM4EMEN1KMT2A | |
| SCHEMBL4199704 | 0.80 | POLB (0.45) | POLBMEN1KMT2ASIGMAR1SMN1; SMN2 | |
| SCHEMBL4199707 | 0.80 | POLB (0.45) | POLBMEN1KMT2ASIGMAR1SMN1; SMN2 | |
| SCHEMBL4212200 | 0.80 | KCNA5 (0.46) | POLBMEN1KMT2ASMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7488738-B2 | Aminophenoxyacetic acid derivatives and pharmaceutical composition containing thereof | ASUBIO PHARMA CO., LTD. (JP) | 2009-02-10 | — | — | US | disclosed |
| US-7488738-B2 | Aminophenoxyacetic acid derivatives and pharmaceutical composition containing thereof | ASUBIO PHARMA CO., LTD. (JP) | 2009-02-10 | — | — | US | disclosed |