Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKD3 | O94806 | 1/20 | 0.46 |
| ▸ | PRKCG | P05129 | 1/20 | 0.46 |
| ▸ | PRKCB | P05771 | 1/20 | 0.46 |
| ▸ | PRKCA | P17252 | 1/20 | 0.46 |
| ▸ | PRKCH | P24723 | 1/20 | 0.46 |
| ▸ | PRKCI | P41743 | 1/20 | 0.46 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.46 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.46 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.46 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.46 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.46 |
| ▸ | G6PD | P11413 | 4/20 | 0.46 |
| ▸ | TLR4 | O00206 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 3/20 | 0.40 |
| ▸ | CA2 | P00918 | 3/20 | 0.40 |
| ▸ | CA9 | Q16790 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13752014 | 1.00 | PRKD3 (0.46) | PRKD3PRKCGPRKCBPRKCAPRKCH | |
| SCHEMBL17253655 | 1.00 | PRKD3 (0.46) | PRKD3PRKCGPRKCBPRKCAPRKCH | |
| SCHEMBL28205738 | 1.00 | PRKD3 (0.46) | PRKD3PRKCGPRKCBPRKCAPRKCH | |
| SCHEMBL2320839 | 1.00 | PRKD3 (0.46) | PRKD3PRKCGPRKCBPRKCAPRKCH | |
| SCHEMBL12038195 | 1.00 | PRKD3 (0.46) | PRKD3PRKCGPRKCBPRKCAPRKCH | |
| SCHEMBL7146273 | 1.00 | PRKD3 (0.46) | PRKD3PRKCGPRKCBPRKCAPRKCH | |
| SCHEMBL14175697 | 1.00 | PRKD3 (0.46) | PRKD3PRKCGPRKCBPRKCAPRKCH | |
| SCHEMBL7150078 | 1.00 | PRKD3 (0.46) | PRKD3PRKCGPRKCBPRKCAPRKCH | |
| SCHEMBL10291154 | 0.98 | PRKD3 (0.43) | PRKD3PRKCGPRKCBPRKCAPRKCH | |
| SCHEMBL22381248 | 0.88 | TLR4 (0.53) | PRKD3PRKCGPRKCBPRKCAPRKCH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090068151-A1 | Methods and reagents for the enhancement of virus transduction in the bladder epithelium | CELL GENESYS, INC. | 2009-03-12 | — | — | US | disclosed |
| US-20080241105-A1 | Method and reagents for the enhancement of virus transduction in the bladder epithelium | CELL GENESYS, INC. | 2008-10-02 | — | — | US | disclosed |
| US-20080076703-A1 | Compositions and methods for the enhanced uptake of therapeutic agents through the bladder epithelium | CELL GENESYS, INC. (US) | 2008-03-27 | — | — | US | disclosed |
| US-7267815-B2 | Methods and reagents for the enhancement of virus transduction in the bladder epithelium | CELL GENESYS, INC. (US) | 2007-09-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080076703-A1 | Compositions and methods for the enhanced uptake of therapeutic agents through the bladder epithelium | MUC1, SLC17A5, CD44 | PRKD3 3889/4885PRKCG 2378/4885PRKCB 1881/4885 |
| US-20090068151-A1 | Methods and reagents for the enhancement of virus transduction in the bladder epithelium | EGFR, MUC1, PLAUR | PRKD3 4033/4885PRKCG 1772/4885PRKCB 1053/4885 |
| US-20080241105-A1 | Method and reagents for the enhancement of virus transduction in the bladder epithelium | EGFR, MUC1, PLAUR | PRKD3 3964/4885PRKCG 1964/4885PRKCB 1139/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.