SCHEMBL13929985

SCHEMBL13929985

N#Cc1c(N)nc(SCc2csc(Cl)n2)c(C#N)c1-c1ccc(OCCO)cc1

nearest known ligand 0.80

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ADORA1 P30542 20/20 0.80
SLC6A3 Q01959 1/20 0.80

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4423125 0.91 ADORA1 (0.79) ADORA1SLC6A3
SCHEMBL4427399 0.91 ADORA1 (0.67) ADORA1SLC6A3
SCHEMBL4426210 0.90 ADORA1 (0.76) ADORA1SLC6A3
SCHEMBL13930005 0.89 ADORA1 (0.66) ADORA1SLC6A3
Capadenoson SCHEMBL174016 0.89 ADORA1 (1.00) ADORA1SLC6A3
SCHEMBL13998935 0.87 ADORA1 (0.85) ADORA1SLC6A3
SCHEMBL13929523 0.87 ADORA1 (0.72) ADORA1SLC6A3
SCHEMBL13914348 0.86 ADORA1 (0.78) ADORA1SLC6A3
SCHEMBL13930080 0.86 ADORA1 (0.81) ADORA1SLC6A3
SCHEMBL3593912 0.85 ADORA1 (0.78) ADORA1SLC6A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1455785-B1 SUBSTITUTED 2-THIO-3,5-DICYANO-4-PHENYL-6-AMINOPYRIDINES AND THE USE OF THE SAME BAYER HEALTHCARE AG (DE) 2009-03-04 EP disclosed
WO-2007073855-A1 USE OF ADENOSINE A1 RECEPTOR AGONISTS FOR THE PROTECTION OF RENAL CELLS AGAINST TOXIC EFFECTS CAUSED BY AMINOGLYCOSIDES DURING TREATMENT OF INFECTIOUS DISEASES BAYER HEALTHCARE AG (DE) 2007-07-05 WO disclosed