Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 17/20 | 0.64 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.51 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4472864 | 0.91 | KCNH2 (0.63) | KCNH2SLC6A3 | |
| SCHEMBL4459459 | 0.90 | KCNH2 (0.62) | KCNH2SLC6A3 | |
| SCHEMBL4459462 | 0.90 | KCNH2 (0.62) | KCNH2SLC6A3 | |
| SCHEMBL4459633 | 0.90 | KCNH2 (0.62) | KCNH2SLC6A3 | |
| SCHEMBL13932708 | 0.87 | KCNH2 (0.63) | KCNH2 | |
| SCHEMBL4472878 | 0.80 | KCNH2 (0.59) | KCNH2SLC6A3HDAC6 | |
| SCHEMBL4475467 | 0.79 | KCNH2 (0.54) | KCNH2SLC6A3 | |
| SCHEMBL4457001 | 0.79 | KCNH2 (0.54) | KCNH2SLC6A3 | |
| SCHEMBL4456995 | 0.79 | KCNH2 (0.54) | KCNH2SLC6A3 | |
| SCHEMBL5634837 | 0.79 | KCNH2 (1.00) | KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7511077-B2 | Diamine calcium channel blockers | NEUROMED PHARMACEUTICALS LTD. (CA) | 2009-03-31 | — | — | US | disclosed |