Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.55 |
| ▸ | ATM | Q13315 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | CNR2 | P34972 | 3/20 | 0.44 |
| ▸ | TOP2A | P11388 | 2/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 2/20 | 0.41 |
| ▸ | PPARA | Q07869 | 1/20 | 0.41 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.41 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.41 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13933056 | 0.86 | TSHR (0.59) | TSHRCYP3A4TDP1ATMALDH1A1 | |
| SCHEMBL13612277 | 0.85 | TSHR (0.60) | TSHRCYP3A4TDP1ATMALDH1A1 | |
| SCHEMBL13933046 | 0.85 | TOP2A (0.50) | TSHRCNR2TOP2APPARGPPARA | |
| SCHEMBL13933045 | 0.85 | TOP2A (0.50) | TSHRCNR2TOP2APPARGPPARA | |
| SCHEMBL13933062 | 0.84 | CYP3A4 (0.59) | TSHRCYP3A4TDP1ATMALDH1A1 | |
| SCHEMBL14566060 | 0.83 | TDP1 (0.57) | TSHRCYP3A4TDP1ATMALDH1A1 | |
| SCHEMBL14566004 | 0.82 | CYP3A4 (0.56) | TSHRCYP3A4TDP1ATMALDH1A1 | |
| SCHEMBL1086969 | 0.82 | TSHR (0.56) | TSHRCYP3A4TDP1ATMALDH1A1 | |
| SCHEMBL13933023 | 0.82 | CYP3A4 (0.56) | TSHRCYP3A4TDP1ATMALDH1A1 | |
| SCHEMBL3761372 | 0.76 | ALDH1A1 (0.43) | TDP1ATMALDH1A1CNR2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7485604-B2 | Lubricant composition and method for using and preparing thereof | FUJIFILM CORPORATION (JP) | 2009-02-03 | — | — | US | disclosed |