Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGKA | P23743 | 1/20 | 0.50 |
| ▸ | PLA2G4B | P0C869 | 4/20 | 0.46 |
| ▸ | CNR2 | P34972 | 3/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | TLR2 | O60603 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.43 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.43 |
| ▸ | RELA | Q04206 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.42 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.42 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | P2RY10 | O00398 | 1/20 | 0.42 |
| ▸ | RARB | P10826 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13933126 | 0.93 | DGKA (0.51) | DGKAPLA2G4BCNR2TP53TSHR | |
| SCHEMBL13933102 | 0.87 | MAPT (0.52) | DGKAPLA2G4BCNR2TP53TSHR | |
| SCHEMBL13933137 | 0.86 | DGKA (0.54) | DGKAPLA2G4BCNR2PRSS1PRSS2 | |
| SCHEMBL13933080 | 0.85 | DGKA (0.55) | DGKAPLA2G4BCNR2TP53TSHR | |
| SCHEMBL14566053 | 0.81 | DGKA (0.57) | DGKAPLA2G4BCNR2TP53TSHR | |
| SCHEMBL13854770 | 0.81 | DGKA (0.57) | DGKAPLA2G4BCNR2TP53TSHR | |
| SCHEMBL13933127 | 0.81 | CYP3A4 (0.57) | CNR2TSHRTLR2LMNAPRSS1 | |
| SCHEMBL13933123 | 0.81 | PDE3B (0.48) | LMNAMAPT | |
| SCHEMBL13612539 | 0.79 | DGKA (0.54) | DGKAPLA2G4BCNR2TP53TSHR | |
| SCHEMBL14163924 | 0.79 | DGKA (0.54) | DGKAPLA2G4BCNR2TP53TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7485604-B2 | Lubricant composition and method for using and preparing thereof | FUJIFILM CORPORATION (JP) | 2009-02-03 | — | — | US | disclosed |