Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 4/20 | 0.66 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.66 |
| ▸ | LMNA | P02545 | 2/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.54 |
| ▸ | MEN1 | O00255 | 5/20 | 0.54 |
| ▸ | MAPT | P10636 | 4/20 | 0.54 |
| ▸ | ABCG2 | Q9UNQ0 | 3/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | ATM | Q13315 | 1/20 | 0.54 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | GBA1 | P04062 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3720836 | 0.85 | ADORA2A (0.79) | ADORA2AADORA1LMNAKMT2AMEN1 | |
| SCHEMBL7913550 | 0.85 | LMNA (0.73) | ADORA2AADORA1LMNAKMT2AMEN1 | |
| SCHEMBL10942195 | 0.82 | ABCG2 (0.47) | ADORA2AADORA1LMNAKMT2AMEN1 | |
| SCHEMBL16189460 | 0.81 | LMNA (0.68) | LMNAKMT2AMEN1MAPTABCG2 | |
| SCHEMBL16189618 | 0.81 | LMNA (0.68) | LMNAKMT2AMEN1MAPTABCG2 | |
| SCHEMBL28859110 | 0.81 | ADORA2A (0.47) | ADORA2AADORA1LMNAKMT2AMEN1 | |
| SCHEMBL17511922 | 0.79 | LMNA (0.66) | LMNAKMT2AMEN1MAPTABCG2 | |
| SCHEMBL16189220 | 0.79 | LMNA (0.66) | LMNAKMT2AMEN1MAPTABCG2 | |
| SCHEMBL17511924 | 0.79 | LMNA (0.66) | LMNAKMT2AMEN1MAPTABCG2 | |
| SCHEMBL1104801 | 0.79 | LMNA (0.66) | ADORA2AADORA1LMNAKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020184906-A1 | ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE USING SAME | 두산솔루스 주식회사 | 2020-09-17 | — | — | WO | disclosed |
| US-7501407-B2 | Pyrimidine A2B selective antagonist compounds, their synthesis and use | OSI PHARMACEUTICALS, INC. (US) | 2009-03-10 | — | — | US | disclosed |