SCHEMBL139339

SCHEMBL139339

COC(=O)c1ccc(C(=O)Oc2ccc(C3(c4ccc(OC)cc4)CCCCC3)cc2)cc1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 1/20 0.57
CA2 P00918 1/20 0.57
KMT2A Q03164 7/20 0.50
LMNA P02545 4/20 0.49
SMN1; SMN2 Q16637 2/20 0.49
CYP2C9 P11712 2/20 0.49
CYP1A2 P05177 1/20 0.49
CYP2C19 P33261 1/20 0.49
MAPT P10636 6/20 0.48
KDM4E B2RXH2 5/20 0.48
MEN1 O00255 1/20 0.48
NPSR1 Q6W5P4 1/20 0.47
TDP1 Q9NUW8 1/20 0.47
ACR P10323 3/20 0.47
PRSS1 P07477 2/20 0.47
HGFAC Q04756 1/20 0.47
GFER P55789 1/20 0.47
HPGD P15428 1/20 0.46
ALDH1A1 P00352 3/20 0.46
ADORA3 P0DMS8 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16775320 0.91 SLC6A2 (0.51) CA1CA2KMT2ALMNASMN1; SMN2
SCHEMBL12345968 0.91 KMT2A (0.48) CA1CA2KMT2ALMNASMN1; SMN2
SCHEMBL13864906 0.91 TDP1 (0.53) CA1CA2KMT2AMAPTKDM4E
SCHEMBL12356802 0.90 CA1 (0.66) CA1CA2KMT2ALMNASMN1; SMN2
SCHEMBL2718813 0.89 KMT2A (0.50) KMT2ALMNASMN1; SMN2CYP2C9CYP1A2
SCHEMBL14580087 0.88 LMNA (0.50) KMT2ALMNASMN1; SMN2CYP2C9CYP1A2
SCHEMBL12404396 0.87 MAPT (0.46) CA1CA2KMT2ALMNASMN1; SMN2
SCHEMBL17066141 0.87 KMT2A (0.45) CA1CA2KMT2ALMNASMN1; SMN2
SCHEMBL19863504 0.87 KMT2A (0.45) CA1CA2KMT2ALMNASMN1; SMN2
SCHEMBL13030420 0.87 TDP1 (0.49) CA1CA2KMT2AMAPTKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180024449-A1 PHOTORECEPTOR FOR ELECTROPHOTOGRAPHY, METHOD FOR MANUFACTURING THE SAME, AND ELECTROPHOTOGRAPHIC DEVICE FUJI ELECTRIC CO., LTD. (JP) 2018-01-25 US disclosed
US-9442400-B2 Electrophotographic photoreceptor including a copolymer polyarylate resin, production method therefor, electrophotographic device including the photoreceptor, and production method for the copolymer polyarylate resin FUJI ELECTRIC CO., LTD. (JP) 2016-09-13 US disclosed
US-20150079510-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, PRODUCTION METHOD THEREFOR, ELECTROPHOTOGRAPHIC DEVICE, AND PRODUCTION METHOD FOR COPOLYMER POLYARYLATE RESIN FUJI ELECTRIC CO., LTD. (JP) 2015-03-19 US disclosed
US-8404414-B2 Electrophotographic photoconductor and manufacturing method thereof FUJI ELECTRIC CO., LTD. (JP) 2013-03-26 US disclosed
US-20120058422-A1 PHOTORECEPTOR FOR ELECTROPHOTOGRAPHY, PROCESS FOR PRODUCING THE SAME, AND ELECTROPHOTOGRAPHIC APPARATUS FUJI ELECTRIC CO., LTD (JP) 2012-03-08 US disclosed
US-20110189603-A1 ELECTROPHOTOGRAPHIC PHOTOCONDUCTOR AND MANUFACTURING METHOD THEREOF FUJI ELECTRIC SYSTEMS CO., LTD. (JP) 2011-08-04 US disclosed