Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 2/20 | 0.59 |
| ▸ | HRH1 | P35367 | 2/20 | 0.59 |
| ▸ | SLC6A3 | Q01959 | 6/20 | 0.48 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.48 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.45 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.44 |
| ▸ | MITF | O75030 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | CNR1 | P21554 | 1/20 | 0.43 |
| ▸ | CNR2 | P34972 | 1/20 | 0.43 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.43 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.43 |
| ▸ | XBP1 | P17861 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11583277 | 0.93 | HTR2A (0.69) | HTR2AHRH1SLC6A3CACNA1BSCN5A | |
| SCHEMBL6411629 | 0.85 | HTR2A (0.67) | HTR2AHRH1SLC6A3CACNA1BSLC6A4 | |
| SCHEMBL25771917 | 0.80 | SLC6A4 (0.41) | HTR2AHRH1SLC6A3CACNA1BSCN5A | |
| SCHEMBL14288444 | 0.79 | TBXA2R (0.46) | HTR2ASLC6A3CACNA1BSCN5AMAPK1 | |
| SCHEMBL7789674 | 0.77 | CYP19A1 (0.46) | SLC6A3CACNA1BSCN5AMITFLMNA | |
| SCHEMBL16805893 | 0.76 | MEN1 (0.50) | HTR2AHRH1CACNA1BSLC6A4TAAR1 | |
| SCHEMBL5089274 | 0.76 | CYP19A1 (0.45) | SLC6A3CACNA1BSCN5ALMNAHTT | |
| SCHEMBL6902789 | 0.76 | CYP19A1 (0.45) | SLC6A3CACNA1BSCN5ALMNAHTT | |
| SCHEMBL5092009 | 0.76 | HRH1 (0.55) | HTR2AHRH1SLC6A3SCN5ATAAR1 | |
| SCHEMBL8251123 | 0.76 | HRH1 (0.55) | HTR2AHRH1SLC6A3SCN5ATAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7507760-B2 | N-type calcium channel blockers | NEUROMED PHARMACEUTICALS LTD. (CA) | 2009-03-24 | — | — | US | disclosed |