Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 1/20 | 0.69 |
| ▸ | NAT1 | P18440 | 3/20 | 0.60 |
| ▸ | PTP4A3 | O75365 | 4/20 | 0.59 |
| ▸ | HPGD | P15428 | 4/20 | 0.56 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.56 |
| ▸ | PIM1 | P11309 | 4/20 | 0.54 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.51 |
| ▸ | PPARG | P37231 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10090184 | 0.87 | PTP4A3 (0.65) | GSK3BPTP4A3HPGDADAMTS5PIM1 | |
| SCHEMBL2064983 | 0.87 | PTP4A3 (0.65) | GSK3BPTP4A3HPGDADAMTS5PIM1 | |
| SCHEMBL2064984 | 0.87 | PTP4A3 (0.65) | GSK3BPTP4A3HPGDADAMTS5PIM1 | |
| SCHEMBL18102857 | 0.80 | GSK3B (0.77) | GSK3BNAT1PTP4A3PIM1PDE4B | |
| SCHEMBL18102849 | 0.79 | GSK3B (0.75) | GSK3BNAT1PTP4A3PIM1PDE4B | |
| SCHEMBL19999112 | 0.79 | NAT1 (0.81) | GSK3BNAT1PTP4A3PIM1PDE4B | |
| SCHEMBL18103046 | 0.78 | GSK3B (0.73) | GSK3BNAT1PTP4A3PIM1PDE4B | |
| SCHEMBL18102860 | 0.78 | GSK3B (0.73) | GSK3BNAT1PTP4A3PIM1PDE4B | |
| SCHEMBL2064980 | 0.78 | PTP4A3 (0.83) | GSK3BNAT1PTP4A3HPGDADAMTS5 | |
| SCHEMBL10090211 | 0.78 | PTP4A3 (0.83) | GSK3BNAT1PTP4A3HPGDADAMTS5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090042872-A1 | Rhodanine Derivatives, a Process for the Preparation Thereof and Pharmaceutical Composition Containing the Same | KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY (KR) | 2009-02-12 | — | — | US | disclosed |
| US-20090042872-A1 | Rhodanine Derivatives, a Process for the Preparation Thereof and Pharmaceutical Composition Containing the Same | KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY (KR) | 2009-02-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090042872-A1 | Rhodanine Derivatives, a Process for the Preparation Thereof and Pharmaceutical Composition Containing the Same | PTPRR, PTPRG, PTPRS | GSK3B 390/4885NAT1 4105/4885PTP4A3 28/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.