SCHEMBL13936444

SCHEMBL13936444

CC(C)(C)OC(=O)NCCOCCOCCOCC(=O)NCCCC[C@H](NC(=O)COCCOCCOCCNC(=O)OC(C)(C)C)C(=O)O

nearest known ligand 0.55

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
▸ GLP1R P43220 8/20 0.55
▸ MEN1 O00255 2/20 0.49
▸ KMT2A Q03164 2/20 0.49
▸ GAA P10253 1/20 0.49
▸ TDP1 Q9NUW8 2/20 0.42
▸ SUCNR1 Q9BXA5 2/20 0.41
▸ C3AR1 Q16581 1/20 0.40
▸ ATM Q13315 1/20 0.40
▸ CA1 P00915 4/20 0.39
▸ CA2 P00918 4/20 0.39
▸ CA12 O43570 2/20 0.39
▸ CA9 Q16790 2/20 0.39
▸ POLB P06746 1/20 0.39
▸ NPSR1 Q6W5P4 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13936447 1.00 GLP1R (0.55) GLP1RMEN1KMT2AGAATDP1
SCHEMBL13936449 1.00 GLP1R (0.55) GLP1RMEN1KMT2AGAATDP1
SCHEMBL13936445 1.00 GLP1R (0.55) GLP1RMEN1KMT2AGAATDP1
SCHEMBL3485751 0.90 GLP1R (0.45) GLP1RMEN1KMT2AGAATDP1
SCHEMBL3485748 0.90 GLP1R (0.45) GLP1RMEN1KMT2AGAATDP1
SCHEMBL20797923 0.90 MEN1 (0.50) GLP1RMEN1KMT2AGAATDP1
SCHEMBL20797924 0.90 MEN1 (0.50) GLP1RMEN1KMT2AGAATDP1
SCHEMBL13936448 0.89 GLP1R (0.54) GLP1RMEN1KMT2AGAATDP1
SCHEMBL13936450 0.89 GLP1R (0.54) GLP1RMEN1KMT2AGAATDP1
SCHEMBL13699549 0.87 GLP1R (0.56) GLP1RMEN1KMT2AGAATDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090036353-A1 Insulin Derivatives Conjugated with Structurally Well Defined Branched Polymers NOVO NORDISK A/S (DK) 2009-02-05 — — US disclosed
US-20090036353-A1 Insulin Derivatives Conjugated with Structurally Well Defined Branched Polymers NOVO NORDISK A/S (DK) 2009-02-05 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090036353-A1 Insulin Derivatives Conjugated with Structurally Well Defined Branched Polymers INSR, IAPP, IGF1R GLP1R 14/4885MEN1 278/4885KMT2A 4457/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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