Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | LIN28A | Q9H9Z2 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13955268 | 0.86 | TDP1 (0.47) | TDP1CYP2C19CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL13936666 | 0.85 | MAPT (0.50) | TDP1CYP2C19CYP1A2SMN1; SMN2MAPT | |
| SCHEMBL13936660 | 0.85 | MAPT (0.44) | TDP1SMN1; SMN2MAPTLIN28AALDH1A1 | |
| SCHEMBL13936661 | 0.85 | MAPT (0.44) | TDP1CYP2C19CYP1A2KCNH2SMN1; SMN2 | |
| SCHEMBL13936663 | 0.85 | MAPT (0.44) | TDP1CYP2C19CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL13936668 | 0.83 | TSHR (0.45) | TDP1SMN1; SMN2MAPTLIN28ARAB9A | |
| SCHEMBL5052519 | 0.79 | TDP1 (0.51) | TDP1CYP2C19CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL13936671 | 0.75 | MAPT (0.46) | TDP1CYP2C19KCNH2SMN1; SMN2MAPT | |
| SCHEMBL31171955 | 0.74 | MAPT (0.61) | TDP1CYP2C19CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL31171947 | 0.74 | MAPT (0.61) | TDP1CYP2C19CYP1A2CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7488820-B2 | Naphthofluorescein-based metal sensors, and methods of making and using the same | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2009-02-10 | — | — | US | disclosed |
| US-7399639-B2 | Sensors, and methods of making and using the same | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2008-07-15 | — | — | US | disclosed |
| US-7399639-B2 | Sensors, and methods of making and using the same | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2008-07-15 | — | — | US | disclosed |