Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | LIN28A | Q9H9Z2 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | SYK | P43405 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.41 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13955392 | 0.86 | TSHR (0.47) | TSHRKMT2AMAPTSMN1; SMN2LIN28A | |
| SCHEMBL13936666 | 0.83 | MAPT (0.50) | TSHRKMT2AMAPTSMN1; SMN2LIN28A | |
| SCHEMBL13936661 | 0.83 | MAPT (0.44) | TSHRKMT2AMAPTSMN1; SMN2LIN28A | |
| SCHEMBL13936663 | 0.83 | MAPT (0.44) | MAPTSMN1; SMN2LIN28ATDP1KDM4E | |
| SCHEMBL13936660 | 0.83 | MAPT (0.44) | TSHRKMT2AMAPTSMN1; SMN2LIN28A | |
| SCHEMBL13936664 | 0.83 | TDP1 (0.44) | TSHRKMT2AMAPTSMN1; SMN2LIN28A | |
| SCHEMBL28683062 | 0.81 | KDM4E (0.48) | TSHRMAPTSMN1; SMN2LIN28ATDP1 | |
| SCHEMBL5050033 | 0.81 | CHRNA7 (0.49) | MAPTSMN1; SMN2LIN28ATDP1CHRNA7 | |
| SCHEMBL22992734 | 0.77 | MAPT (0.49) | KMT2AMAPTSMN1; SMN2LIN28ATDP1 | |
| SCHEMBL29383167 | 0.77 | MAPT (0.49) | KMT2AMAPTSMN1; SMN2LIN28ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7488820-B2 | Naphthofluorescein-based metal sensors, and methods of making and using the same | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2009-02-10 | — | — | US | disclosed |
| US-7399639-B2 | Sensors, and methods of making and using the same | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2008-07-15 | — | — | US | disclosed |
| US-7399639-B2 | Sensors, and methods of making and using the same | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2008-07-15 | — | — | US | disclosed |