⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13373220 | 0.74 | — | — | |
| Hydrochloric Acid SCHEMBL22771601 | 0.72 | — | — | |
| Hydrochloric Acid SCHEMBL22771602 | 0.72 | — | — | |
| SCHEMBL3040468 | 0.71 | — | — | |
| SCHEMBL18951894 | 0.70 | — | — | |
| Hydrochloric Acid SCHEMBL22771756 | 0.69 | ADH1B (0.40) | — | |
| Hydrochloric Acid SCHEMBL22771757 | 0.69 | ADH1B (0.40) | — | |
| SCHEMBL18760813 | 0.67 | — | — | |
| SCHEMBL13005211 | 0.67 | — | — | |
| SCHEMBL25918248 | 0.67 | TSHR (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2025671-A1 | NITROGEN-CONTAINING HETEROCYCLIC COMPOUND AND THROMBOPOIETIN RECEPTOR ACTIVATOR | Nissan Chemical Industries, Ltd. (JP) | 2009-02-18 | — | — | EP | disclosed |
| WO-2007010954-A1 | THIOPHENE COMPOUNDS AND THROMBOPOIETIN RECEPTOR ACTIVATORS | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2007-01-25 | — | — | WO | disclosed |