SCHEMBL13939726

SCHEMBL13939726

Cc1noc(C)c1Cn1cc(N2C(=O)C(CC3=CCCC=C3)N(C)C2=C2CC2)cn1

nearest known ligand 0.56

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ TAS2R8 Q9NYW2 20/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1279459 0.72 TAS2R8 (1.00) TAS2R8
SCHEMBL12290402 0.72 TAS2R8 (0.84) TAS2R8
SCHEMBL18351062 0.71 TAS2R8 (0.74) TAS2R8
SCHEMBL1278701 0.70 TAS2R8 (1.00) TAS2R8
SCHEMBL11923770 0.69 TAS2R8 (0.68) TAS2R8
SCHEMBL12289358 0.69 TAS2R8 (0.70) TAS2R8
SCHEMBL18351060 0.68 TAS2R8 (0.68) TAS2R8
SCHEMBL13939313 0.68 TAS2R8 (0.79) TAS2R8
SCHEMBL1279124 0.68 TAS2R8 (1.00) TAS2R8
SCHEMBL11924505 0.67 TAS2R8 (0.67) TAS2R8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2009025793-A2 HUMAN T2R BITTERNESS RECEPTORS AND USES THEREOF SENOMYX, INC. (US) 2009-02-26 — — WO disclosed
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