Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | DRD3 | P35462 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | APLNR | P35414 | 1/20 | 0.33 |
| ▸ | CTSD | P07339 | 1/20 | 0.33 |
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.33 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3988073 | 0.91 | ALDH1A1 (0.39) | ALDH1A1GAAALOX15MAPTPOLB | |
| SCHEMBL3994178 | 0.88 | DRD1 (0.33) | ALDH1A1GAALMNATHRB | |
| SCHEMBL3987953 | 0.87 | ALDH1A1 (0.40) | ALDH1A1MAPTPOLBLMNATSHR | |
| SCHEMBL3990147 | 0.85 | HCRTR1 (0.32) | MAPTPOLBCTSDBACE1BACE2 | |
| SCHEMBL3988334 | 0.84 | NPC1 (0.34) | ALDH1A1GAAPOLBDRD2THRB | |
| SCHEMBL3985193 | 0.84 | MAPT (0.37) | ALDH1A1GAAALOX15MAPTPOLB | |
| SCHEMBL3990626 | 0.83 | ALDH1A1 (0.36) | ALDH1A1POLBLMNA | |
| SCHEMBL3987990 | 0.82 | ALDH1A1 (0.35) | ALDH1A1 | |
| SCHEMBL3987142 | 0.81 | NTRK1 (0.37) | ALDH1A1GAAMAPTPOLBLMNA | |
| SCHEMBL3992344 | 0.81 | PDE5A (0.33) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7473790-B2 | Inhibitors of hepatitis C virus RNA-dependent RNA polymerase, and compositions and treatments using the same | PFIZER INC. (US) | 2009-01-06 | — | — | US | disclosed |