SCHEMBL13940179

SCHEMBL13940179

CCc1ccccc1CN1CC(=O)N(c2cnn(Cc3c(C)noc3C)c2)C1=O

nearest known ligand 0.86

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ TAS2R8 Q9NYW2 20/20 0.86

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13637759 0.93 TAS2R8 (0.83) TAS2R8
SCHEMBL11924258 0.93 TAS2R8 (0.83) TAS2R8
SCHEMBL1279375 0.92 TAS2R8 (1.00) TAS2R8
SCHEMBL1278899 0.91 TAS2R8 (1.00) TAS2R8
SCHEMBL1279376 0.91 TAS2R8 (1.00) TAS2R8
SCHEMBL1278714 0.91 TAS2R8 (1.00) TAS2R8
SCHEMBL13939291 0.90 TAS2R8 (0.79) TAS2R8
SCHEMBL13940180 0.89 TAS2R8 (0.78) TAS2R8
SCHEMBL12062612 0.89 TAS2R8 (0.80) TAS2R8
SCHEMBL1278994 0.89 TAS2R8 (1.00) TAS2R8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2009025793-A2 HUMAN T2R BITTERNESS RECEPTORS AND USES THEREOF SENOMYX, INC. (US) 2009-02-26 — — WO disclosed
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